
Thalidomide-O-amido-C6-NH2 hydrochloride
CAS No. 2376990-31-5
Thalidomide-O-amido-C6-NH2 hydrochloride ( —— )
产品货号. M27019 CAS No. 2376990-31-5
沙利度胺-O-酰胺基-C6-NH2 盐酸盐是一种合成的 E3 连接酶配体-接头缀合物,其中包含基于沙利度胺的 cereblon 配体和接头。它可用于PROTAC的合成。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥3038 | 有现货 |
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10MG | ¥4512 | 有现货 |
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25MG | ¥7266 | 有现货 |
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50MG | ¥9963 | 有现货 |
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100MG | ¥13365 | 有现货 |
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500MG | ¥26649 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Thalidomide-O-amido-C6-NH2 hydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述沙利度胺-O-酰胺基-C6-NH2 盐酸盐是一种合成的 E3 连接酶配体-接头缀合物,其中包含基于沙利度胺的 cereblon 配体和接头。它可用于PROTAC的合成。
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产品描述Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. It can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体P450
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研究领域——
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适应症——
化学信息
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CAS Number2376990-31-5
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分子量466.92
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分子式C21H27ClN4O6
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纯度>98% (HPLC)
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溶解度——
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SMILESCl.NCCCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Levron, J.C., et al. Pharmacokinetic study of 2,3-dichloro 4- (2-thienyl keto14C) phenoxyacetic acid (tienilic acid) in animals. European Journal of Drug Metabolism and Pharmacokinetics 2, 107–120 (1977).
产品手册




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